patented pomegranate extract
standardized to punicalagins.
THIS SITE IS NOT INTENDED FOR CONSUMER USE.
VERDURE SCIENCES, INC.
ANECDOTAL ANTIOXIDANTS: FOUNDATIONS OF POMEGRANATE RESEARCH AND QUALITY
When medical researchers at a prestigious US university were looking at various parts of the diet to find the best antioxidant candidates to promote cardiovascular health, healthy aging, and longevity, pomegranate was found to have the top activity in their models. They set about to figure out what it was, exactly, in pomegranate that makes it so active.
Researchers found a group of potent antioxidants called punicalagins. Punicalagins are
ellagitannin polyphenols that are among the most ferocious scavengers of free radicals,
or unstable molecules that can cause damage to the body over time. They also display
some other interesting activities, such as potent modulation of inflammation and
protective effects of DNA and cellular signaling. Punicalagins are unique because they
are able to break apart, or hydrolyze, into ‘daughter’ polyphenols (such as ellagic acid)
once in the bloodstream, and extensively metabolize and absorb into target tissues.
However, there is a catch to pomegranate bioavailability. The researchers found that
if punicalagins hydrolyze before they enter the bloodstream, their daughter molecules
do not absorb; they need to be attached to the ‘parent’ polyphenol to be bioavailable.
While punicalagins are the primary factor contributing to the high antioxidant potency of pomegranate juice, pure 100% pomegranate juice can be expensive and is not standardized to contain consistent amounts of punicalagins. In fact, research has shown pomegranate juice can have more than 100% variability in polyphenol content, in addition to a high sugar and calorie content.
A shrub or small tree that can grow 20-30 feet high but usually has an average of 12 to 16 feet. The exceptionally long-lived pomegranate tree takes about nine years to reach maturity and has many spiny branches. The flowers grow on the branch tips in clusters. At summers’ end, the petals of the flowers fall away, revealing the iconic pomegranate crowns. The pericarp, or rind, of the protective fruit contains chambers that house small edible seeds called arils. The ruby-like arils are deliciously sweet and tart.
The pomegranate is native to the region from India to Iran and has been cultivated over the
whole Mediterranean region since ancient times. It is widely cultivated throughout India and
the drier parts of southeast Asia, Malaya, and the East Indies and tropical Africa, as the
pomegranate tree is drought-tolerant. The tree was then introduced to California by Spanish
settlers around 1769.
Harvest season begins in September and ends in February for the Northern Hemisphere,
and typically lasts from March to May in the Southern Hemisphere. The pomegranates ripen
roughly six to seven months after flowering. Growers generally consider the fruit ready for
harvest if it makes a metallic sound when tapped. They must be hand-picked before over
maturity when the fruits tend to crack open. They should not be pulled off but clipped close
to the base so as to leave no stem, as the stems can cause damage in handling and shipping.
Too much sun exposure causes sunscald-brown, rusted blemishes and roughening of the rind.
Please note that the physiological activity of the ingredient(s) described herein is supported by the referenced clinical trial report(s). Marketers of finished products containing the ingredient(s) described herein are responsible for determining whether claims made for such products are lawful and in compliance with the laws of the country in which they will market the products.
OUR ROOTS: A FAMILY OF INGREDIENTS
Verdure Sciences® is a supplier of botanical extracts through the integration of agricultural, production, and research platforms. Our emphasis is on developing scientifically backed botanical extracts through clinical initiatives.
Our commitment to quality control and our global procurement network allows us to offer new and traditional products with traceable and scientific validation.
Dedication to our customer needs is second to none. We proudly serve and supply customers all over the globe with botanical ingredients.
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THE ARIL OF MY EYE
The pomegranate (Punica granatum) is one of the oldest fruits known to man. The pomegranate tree is a rounded shrub that typically grows 12 to 28 feet high and is native to the modern-day regions of India and Iran. The rich, red fruit is surrounded by a hard leathery skin that protects a delicate sweetly favored interior. It is known to be rich in antioxidants, which have, in turn, shown protective against free radicals. In particular, the antioxidant punicalagin is special to pomegranates.
Verdure Sciences, Longvida (US Patent 9192644, EP Patent 1993365; additional patents pending), Bacognize, Calzbone, Pomella (US Patents 7638640, 7897791, and 7919636; EP Patent 1734949; additional patents pending), Tinofend, and WokVel are registered trademarks of Verdure Sciences, Inc. Cinnagest, Factor21, Lutevida, Rejuna, Thymocid, Gingerize, VBATS, VerdeMedica, SLP, and SLCP are trademarks of Verdure Sciences, Inc. All Rights Reserved. © 2016 Verdure Sciences.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.