patented pomegranate extract

standardized to punicalagins.

THIS SITE IS NOT INTENDED FOR CONSUMER USE.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Botanical waste products are recycled (above) to provide energy for the manufacturing process, reducing outside energy use several fold compared to conventional extraction facilities. Additionally, excess botanical waste products are donated to local farmers and used as a substitute for synthetic fertilizers. A proprietary internal wastewater treatment facility cleans and recycles water, eliminating runoff to the local watershed. Furthermore, new sustainability efforts are in testing and implementation phases, as environmental responsibility and sustainability are a critical addition to our corporate values.

Verdure Sciences, Longvida (US Patent 9192644, EP Patent 1993365; additional patents pending), Bacognize, Calzbone, Pomella (US Patents 7638640, 7897791, and 7919636; EP Patent 1734949; additional patents pending), Tinofend, and WokVel are registered trademarks of Verdure Sciences, Inc. Cinnagest,  Factor21, Lutevida, Rejuna, Thymocid, Gingerize, VBATS, VerdeMedica, SLP, and SLCP are trademarks of Verdure Sciences, Inc. All Rights Reserved. © 2016 Verdure Sciences.

QUALITY CONTROL

POMELLA® EXTRACT: THE POMEGRANATE GOLD STANDARD       

TRACEABILITY, CONTROL, AND CONSISTENCY OF POMELLA® RAW MATERIALS
A large part of our quality control is knowing where our raw materials come from – traceability and transparency are primary concerns here at Verdure Sciences®. Thanks to company contracted farming relationships, some of which are certified organic, a paper trail follows our pomegranate raw materials from the orchards to the factory.

Because we know exactly where our pomegranate fruit comes from, we can offer an

ingredient that complies with industry guidelines for residual pesticides and heavy

metals that is also non-GMO.  Each batch of incoming pomegranate fruit is also verified

by Thin Layer Chromatography, which confirms the identity of the raw materials past

a mere visual inspection.

Through full knowledge and control of the farming and harvesting processes, we can

also offer pomegranates harvested under fair trade practices.

Additionally, part of the Pomella® research process has involved finding the best

cultivar, or cultivated variety, of pomegranate, offering the widest range of associated

health benefits. Through full control of the raw materials, we add an extra level of

assurance that each batch of Pomella Extract is consistent with the associated in vitro

and in vivo research and results.


MANUFACTURING PROCESS
Pomella® Pomegranate Extract is developed as an ingredient for dietary supplements, functional foods, cosmeceuticals, etc. and is available in powder, granule, and other grades. Due to our complete control: from procurement to manufacturing and research, various forms of Pomella can be custom formulated and specially tailored.

The patented and proprietary manufacturing process that preserves the natural, water soluble, polyphenolic ratio of pomegranate fruit according to the strict specifications developed by university research.

Operating under Good Manufacturing Practices (GMP), certified organic (when applicable), ISO, HACCP, Kosher and Halal certified; our hands-free botanicals-only facility does not process pharmaceuticals or other fine chemicals,

and adheres to the highest equipment standards – down to the highest grade of

stainless steel in our extraction vessels – helping to offer contaminant-free

ingredients that are highly consistent from batch to batch.

Our manufacturing facility employs several systems that contribute to environmental

responsibility and sustainability, including recycling, energy efficiency, and internal

water treatment.


QUALITY CONTROL & ANALYTICAL METHODOLOGY
In addition to our vertically integrated control, from the farm to the drum, each

batch of Pomella® Extract must undergo rigorous analyses at both in-house and

independent laboratories, as detailed in our product and manufacturing

specifications.

Selected analyses follow (one or more):

  • Multiple Standardization Fingerprint of Several Polyphenolic Compounds,​ Particularly Punicalagins, using Validated HPLC Methodology and Purified, Validated Standards

  • Non-Specific Colorimetric Methods Such as UV
  • Impurities Performed by USP and Other Recognized Pharmacopoeial Methodologies
  • Enhanced Battery of Physico-Chemical Analyses Performed at Multiple Labs


Ingredients are as good as the methodology behind them; without appropriate methodology it is difficult to know that a product, or ingredient, meets the rigorous specifications, or claims, made. Therefore, we use the recognized, repeatable methods published in peer-reviewed literature, and the most advanced instrumentation available, including one or more of the following: 

  • Atomic Absorption Spectroscopy (AAS), Inductively Coupled Plasma-Mass Spectrometry (ICP/MS), Gas Chromatography/Mass Spectrometry (GC/MS), High-Performance Liquid Chromatography (HPLC), and High Performance Thin Layer Chromatography for Impurities/Chemical Analysis
  • HPLC and HPTLC for Identity and Purity, in Addition to Other Non-Specific Colorimetric Methods such as UV-Vis Spectrometry
  • Liquid Chromatography/Mass Spectrometry (LC/MS or LC/MS/MS) for Trace Compounds and Pharmacokinetic Analyses
  • Bioactivity Analyses using Cell Cultures and Detection Methods such as Enzyme-Linked Immunoassays, Polymerase Chain Reaction (PCR) Techniques, and Immunofluorescence Imaging
  • Clinical Endpoint Analyses using Imaging Tools such as Position Emission Tomography and Magnetic Resonance Imaging

SUSTAINABILITY & ENVIRONMENTAL RESPONSIBILITY
Our drive to preserve nature’s excellence through science extends beyond providing efficacious and safe ingredients that offer tangible health benefits. In an effort to sustain ourselves far into the future, we must make solid contributions to protecting and supporting an environment where this mission remains possible.

Therefore, our mission manifestly includes implementation of a multi-faceted sustainability program. Our sustainability initiatives are all encompassing, from the design of the facility with a large consideration to energy efficiency – with particular regard to solar and wind use to minimize the need for climate controls and lighting – to recycling and fair trade practices.

Please note that the physiological activity of the ingredient(s) described herein is supported by the referenced clinical trial report(s). Marketers of finished products containing the ingredient(s) described herein are responsible for determining whether claims made for such products are lawful and in compliance with the laws of the country in which they will market the products.​